KEGG   Homo sapiens (human): 7222
Entry
7222              CDS       T01001                                 
Symbol
TRPC3, SCA41, TRP3
Name
(RefSeq) transient receptor potential cation channel subfamily C member 3
  KO
K04966  transient receptor potential cation channel subfamily C member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa05017  Spinocerebellar ataxia
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06462  Spinocerebellar ataxia
nt06463  Parkinson disease
nt06466  Pathways of neurodegeneration
nt06528  Calcium signaling
  Element
N00953  mGluR1-TRPC3 signaling pathway
N00955  Mutation-inactivated PRKCG to mGluR1-TRPC3 signaling pathway
N00956  Mutation-activated PRKCG to mGluR1-TRPC3 signaling pathway
N00961  Mutation-activated TRPC3 to mGluR1-TRPC3 signaling pathway
N01741  Ca2+/TRPC3 signaling pathway
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    7222 (TRPC3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    7222 (TRPC3)
   05022 Pathways of neurodegeneration - multiple diseases
    7222 (TRPC3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7222 (TRPC3)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7222 (TRPC3)
SSDB
Motif
Pfam: TRP_2 Ion_trans PKD_channel Ank_2 Ank Ank_4 Ank_3 MFS_4
Other DBs
NCBI-GeneID: 7222
NCBI-ProteinID: NP_001124170
OMIM: 602345
HGNC: 12335
Ensembl: ENSG00000138741
UniProt: Q13507
Structure
Position
4:complement(121874481..121952060)
AA seq 921 aa
MSTKVRKCKEQARVTFPAPEEEEDEGEDEGAEPQRRRRGWRGVNGGLEPRSAPSQREPHG
YCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAA
EYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALL
LAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILA
AHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYL
SLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAIL
NGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIA
IKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDR
FEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQ
LWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARD
KWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMV
FFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIG
YVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPF
SLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNS
ILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATE
ELAILIHKLSEKLNPSMLRCE
NT seq 2766 nt   +upstreamnt  +downstreamnt
atgtccaccaaggtcaggaagtgcaaagaacaagcaagggtgaccttcccggcgccggag
gaggaggaagacgagggcgaggacgagggcgcggagccgcagcgccgccgccggggctgg
aggggcgtcaacggggggctggagccgcgctcggcgccctcgcagcgggagccgcacggc
tactgcccgccgcccttctcccacgggccggacctgtccatggagggaagcccatccctg
agacgcatgacagtgatgcgggagaagggccggcgccaggctgtcaggggcccggccttc
atgttcaatgaccgcggcaccagcctcaccgccgaggaggagcgcttcctcgacgccgcc
gagtacggcaacatcccagtggtgcgcaagatgctggaggagtccaagacgctgaacgtc
aactgcgtggactacatgggccagaacgcgctgcagctggctgtgggcaacgagcacctg
gaggtgaccgagctgctgctcaagaaggagaacctggcgcgcattggcgacgccctgctg
ctcgccatcagcaagggctacgtgcgcatcgtagaggccatcctcaaccaccctggcttc
gcggccagcaagcgtctcactctgagcccctgtgagcaggagctgcaggacgacgacttc
tacgcttacgacgaggacggcacgcgcttctcgccggacatcacccccatcatcctggcg
gcgcactgccagaaatacgaagtggtgcacatgctgctgatgaagggtgccaggatcgag
cggccgcacgactatttctgcaagtgcggggactgcatggagaagcagaggcacgactcc
ttcagccactcacgctcgaggatcaatgcctacaaggggctggccagcccggcttacctc
tcattgtccagcgaggacccggtgcttacggccctagagctcagcaacgagctggccaag
ctggccaacatagagaaggagttcaagaatgactatcggaagctctccatgcaatgcaaa
gactttgtagtgggtgtgctggatctctgccgagactcagaagaggtagaagccattctg
aatggagatctggaatcagcagagcctctggaggtacacaggcacaaagcttcattaagt
cgtgtcaaacttgccattaagtatgaagtcaaaaagtttgtggctcatcccaactgccag
cagcagctcttgacgatctggtatgagaacctctcaggcctaagggagcagaccatagct
atcaagtgtctcgttgtgctggtcgtggccctgggccttccattcctggccattggctac
tggatcgcaccttgcagcaggctggggaaaattctgcgaagcccttttatgaagtttgta
gcacatgcagcttctttcatcatcttcctgggtctgcttgtgttcaatgcctcagacagg
ttcgaaggcatcaccacgctgcccaatatcacagttactgactatcccaaacagatcttc
agggtgaaaaccacccagtttacatggactgaaatgctaattatggtctgggttcttgga
atgatgtggtctgaatgtaaagagctctggctggaaggacctagggaatacattttgcag
ttgtggaatgtgcttgactttgggatgctgtccatcttcattgctgctttcacagccaga
ttcctagctttccttcaggcaacgaaggcacaacagtatgtggacagttacgtccaagag
agtgacctcagtgaagtgacactcccaccagagatacagtatttcacttatgctagagat
aaatggctcccttctgaccctcagattatatctgaaggcctttatgccatagctgttgtg
ctcagcttctctcggattgcgtacatcctccctgcaaatgagagctttggccccctgcag
atctctcttggaaggactgtaaaggacatattcaagttcatggtcctctttattatggtg
ttttttgcctttatgattggcatgttcatactttattcttactaccttggggctaaagtt
aatgctgcttttaccactgtagaagaaagtttcaagactttattttggtcaatatttggg
ttgtctgaagtgacttccgttgtgctcaaatatgatcacaaattcatagaaaatattgga
tacgttctttatggaatatacaatgtaactatggtggtcgttttactcaacatgctaatt
gctatgattaatagctcatatcaagaaattgaggatgacagtgatgtagaatggaagttt
gctcgttcaaaactttggttatcctattttgatgatggaaaaacattacctccacctttc
agtctagttcctagtccaaaatcatttgtttatttcatcatgcgaattgttaactttccc
aaatgcagaaggagaaggcttcagaaggatatagaaatgggaatgggtaactcaaagtcc
aggttaaacctcttcactcagtctaactcaagagtttttgaatcacacagttttaacagc
attctcaatcagccaacacgttatcagcagataatgaaaagacttataaagcggtatgtt
ttgaaagcacaagtagacaaagaaaatgatgaagttaatgaaggtgaattaaaagaaatc
aagcaagatatctccagccttcgttatgaacttttggaagacaagagccaagcaactgag
gaattagccattctaattcataaacttagtgagaaactgaatcccagcatgctgagatgt
gaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (9)   
   KEGG NETWORK (9)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (31)   
   RefSeq(nuc) (13)   
   GenBank (9)   
   EMBL (9)   
3D Structure (8)   
   PDB (8)   
Protein domain (8)   
   Pfam (8)   
All databases (88)   

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